Description

2-Difluoromethylbenzonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a difluoromethyl group and a nitrile moiety, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the difluoromethyl group to modulate pharmacokinetics and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Fluorine Chemistry: An essential reagent for exploring new fluorination methodologies and creating libraries of fluorinated compounds for screening in various applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects at various scales, from gram to kilogram quantities.

Basic Information

Product Name	2-Difluoromethylbenzonitrile
CAS No.	799814-30-5
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	2-(Difluoromethyl)benzonitrile; o-Difluoromethylbenzonitrile; Benzonitrile, 2-(difluoromethyl)-; 2-Cyanobenzyl Difluoride; α,α-Difluoro-o-tolunitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Difluoromethylbenzonitrile is produced and tested under a strict quality management system to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.