Description

2-(Trifluoromethoxy)Benzimidamide is a specialized benzimidamide derivative featuring a trifluoromethoxy substituent, a structural motif of significant interest in advanced organic synthesis. This compound serves as a critical high-purity building block for the development of novel active molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique structure makes it an essential intermediate for researchers and manufacturers focused on creating compounds with enhanced metabolic stability and bioavailability. Target industries include pharmaceutical R&D, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for improved efficacy and environmental profile.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways in academic and industrial research.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied as a high-purity starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-(Trifluoromethoxy)Benzimidamide
CAS No.	784105-47-1
Molecular Formula	C8H6F3N2O
Molecular Weight	203.14 g/mol
Synonyms	2-(Trifluoromethoxy)-1H-benzimidamide; Benzenecarboximidamide, 2-(trifluoromethoxy)-; 2-(Trifluoromethoxy)benzene-1-carboximidamide; α-(Trifluoromethoxy)-1H-benzimidamide; (2-(Trifluoromethoxy)phenyl)methanimidamide
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethoxy)Benzimidamide is manufactured and tested under a strict quality management system to ensure high purity and batch-to-batch consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects with material suitable for research use through to cGMP-grade applications, with documentation available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.