Description

1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane-carbonitrile core substituted with bromo and fluoro groups. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of complex bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the bromo and fluoro substituents contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialized ligands or monomers in the development of functional polymers and advanced materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	749269-73-6
Molecular Formula	C10H7BrFN
Molecular Weight	240.07 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)cyclopropanecarbonitrile; 4-Bromo-3-fluoro-α-(cyanomethyl)benzenemethanol, cyclic acetal with formaldehyde; Cyclopropanecarbonitrile, 1-(4-bromo-3-fluorophenyl)-; 749269-73-6; 1-(4-Bromo-3-fluorophenyl)cyclopropanecarbonitrile; (4-Bromo-3-fluorophenyl)cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carbonitrile adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.