Description

2,3-Difluoro-4-Formylbenzonitrile is a versatile aromatic nitrile building block featuring both formyl and fluorine substituents. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on fluorinated active ingredients, liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated mesogens in display technology due to its polarizable aromatic core and fluorine atoms.
• Organic Electronics: Employed in the research and development of organic semiconductors and electron-transport materials.
• Functional Polymer Monomer: Used to incorporate nitrile and aldehyde functionalities into specialty polymers for advanced material applications.
• Cross-Coupling Reactions: The formyl and cyano groups make it a valuable substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	2,3-Difluoro-4-Formylbenzonitrile
CAS No.	717883-41-5
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	4-Cyano-2,3-difluorobenzaldehyde; 2,3-Difluoro-4-formylbenzonitrile; 2,3-Difluorobenzaldehyde-4-carbonitrile; 4-Formyl-2,3-difluorobenzonitrile; Benzonitrile, 2,3-difluoro-4-formyl-; 2,3-Difluoro-4-cyanobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.