Description

Benzeneacetonitrile, 5-Fluoro-2-Hydroxy- (9Ci) is a specialized fluorinated aromatic nitrile building block, valued for its unique bifunctional reactivity. This compound serves as a critical intermediate in advanced organic synthesis, where its phenolic hydroxyl and nitrile groups offer versatile handles for derivatization. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Complex Ligand Synthesis: Employed in the preparation of specialized chelating agents and ligands for catalytic and material science applications.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and heterocycle formation within university and CRO laboratories.

Basic Information

Product Name	Benzeneacetonitrile, 5-Fluoro-2-Hydroxy- (9Ci)
CAS No.	709025-81-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-2-hydroxybenzyl cyanide; 2-Cyano-4-fluorophenol; (5-Fluoro-2-hydroxyphenyl)acetonitrile; 4-Fluoro-2-(cyanomethyl)phenol; 2-Hydroxy-5-fluorobenzeneacetonitrile; 5-Fluoro-2-hydroxybenzenecetonitrile; 5-Fluoro-2-hydroxyphenylacetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 5-Fluoro-2-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.