Description

Benzenepropanenitrile, β-Fluoro-α-Hydroxy- is a specialized fluorinated nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive nitrile group and a fluorinated hydroxy-substituted carbon chain, makes it a valuable precursor for constructing complex pharmacophores and agrochemical intermediates. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce fluorine atoms and functionalized side chains into target molecules to modulate their biological activity, metabolic stability, and physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to enhance drug potency and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atom and nitrile functionality contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Acts as a building block for fluorinated organic electronic materials, where its structure can influence dielectric anisotropy and molecular alignment.
• Advanced Polymer Chemistry: Employed in the synthesis of specialty polymers and coatings, imparting unique properties such as chemical resistance or specific surface energies.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated molecular probes and tags used in biochemical assays and imaging studies.

Basic Information

Item	Details
Product Name	Benzenepropanenitrile, β-Fluoro-α-Hydroxy-
CAS No.	79963-86-3
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	3-(Fluoromethyl)-3-hydroxy-3-phenylpropanenitrile; 2-Fluoro-1-hydroxy-3-phenylpropionitrile; β-Fluoro-α-hydroxybenzenepropanenitrile; 3-Fluoro-2-hydroxy-2-phenylpropionitrile; (RS)-2-Fluoro-1-hydroxy-3-phenylpropionitrile; (±)-2-Fluoro-1-hydroxy-3-phenylpropionitrile; 79963-86-3; 3-Phenyl-3-fluoro-3-hydroxypropionitrile
EINECS	Contact for details

Quality Control

Our production of Benzenepropanenitrile, β-Fluoro-α-Hydroxy- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.