Description

Cytodex 1 is a microcarrier specifically designed for the large-scale cultivation of anchorage-dependent animal and human cells. This product is essential for enabling high-density cell growth in bioreactors, a critical step in the production of vaccines, monoclonal antibodies, and other biopharmaceuticals. It is a vital tool for research institutions, contract development and manufacturing organizations (CDMOs), and biotechnology companies focused on cell culture and bioprocess development.

Application

• Large-Scale Vaccine Production: Cultivation of virus-producing cell lines (e.g., Vero, MRC-5) for viral vaccine manufacturing.
• Monoclonal Antibody Production: Growth of hybridoma or recombinant mammalian cell lines (e.g., CHO, HEK293) in stirred-tank bioreactors.
• Cell Therapy & Regenerative Medicine: Expansion of stem cells and other therapeutic cell types for clinical applications.
• Recombinant Protein Expression: Scalable production of complex proteins requiring post-translational modifications.
• Bioprocess Development & Optimization: Used in process scale-up studies and media optimization for industrial cell culture.
• Basic Cell Biology Research: Provides a controlled surface for studying cell adhesion, proliferation, and differentiation in vitro.

Basic Information

Product Name	Cytodex 1
CAS No.	79920-52-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dextran Microcarrier; Cross-linked Dextran Microcarrier; DEAE-Dextran Microcarrier; Diethylaminoethyl-Dextran Microcarrier; Microcarrier Beads; Cell Culture Microcarriers; Cytodex® 1; Cytodex 1 Microcarrier
EINECS	Contact for details

Quality Control

Our Cytodex 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency essential for reproducible cell culture performance. Each lot is tested for key parameters including particle size distribution, swelling rate, and functional group density. Certificates of Analysis (COA) detailing these specifications are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white beads
Particle Size Range	131 - 220 μm (dry)
Swelling Factor (in PBS)	Contact for details
Ion Exchange Capacity	1.5 - 2.0 meq/g (dry)
Sterility	Sterilized by gamma irradiation
Endotoxin Level	< 1.0 EU/mL (after swelling)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.