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6,8,11-Trihydroxy-8-(1-Hydroxyethyl)-10-[(4S,5S,6S)-5-Hydroxy-6-Methyl -4-Morpholin-4-Yl-Oxan-2-Yl]Oxy-1-Methoxy-9,10-Dihydro-7H-Tetracene-5, 12-Dione CAS NO 79867-79-1
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CAS No.:79867-79-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6,8,11-Trihydroxy-8-(1-Hydroxyethyl)-10-[(4S,5S,6S)-5-Hydroxy-6-Methyl-4-Morpholin-4-Yl-Oxan-2-Yl]Oxy-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione is a complex, high-purity anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in oncology. It is essential for R&D chemists, process development scientists, and analytical laboratories working on next-generation cancer treatments, antibiotic development, and specialized chemical synthesis.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
- Reference Standard: High-purity material for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
- Biochemical Research: Tool compound for studying DNA intercalation mechanisms, topoisomerase inhibition, and structure-activity relationships (SAR) in medicinal chemistry.
- Process Chemistry: Used in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
- Academic Research: Investigated in university and institutional labs for its biological activity and potential in drug discovery programs.
Basic Information
| Product Name | 6,8,11-Trihydroxy-8-(1-Hydroxyethyl)-10-[(4S,5S,6S)-5-Hydroxy-6-Methyl-4-Morpholin-4-Yl-Oxan-2-Yl]Oxy-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione |
| CAS No. | 79867-79-1 |
| Molecular Formula | C31H37NO12 |
| Molecular Weight | 615.63 g/mol |
| Synonyms | 10-Deoxymethymycin; 10-Deoxymethymycin A; 10-Demethoxymethymycin; 4''-Deoxy-β-rhodomycinone; 4''-Deoxy-β-rhodomycinone derivative; Anthracycline derivative 79867-79-1; (8S,10S)-8-(1-Hydroxyethyl)-10-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione |
| EINECS | Contact for details |
Quality Control
Our 6,8,11-Trihydroxy-8-(1-Hydroxyethyl)-10-[(4S,5S,6S)-5-Hydroxy-6-Methyl-4-Morpholin-4-Yl-Oxan-2-Yl]Oxy-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of related substances. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and pharmaceutical grade requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling and storage must ensure protection from all light exposure to maintain stability and potency.
Specification
| Item | Specification |
|---|---|
| Appearance | Red to orange-red powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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