Description

3'-(4-Methoxy-1-Piperidinyl)-3'-Deaminodaunorubicin is a synthetic derivative of the anthracycline antibiotic daunorubicin, modified at the 3'-position. This structural modification is significant for altering biological activity and physicochemical properties, making it a valuable intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel chemotherapeutic agents and for advanced pharmacological studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anthracycline-based anticancer drugs.
• Biochemical Research: Used as a reference standard or probe compound in studies of DNA intercalation and topoisomerase II inhibition.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aimed at developing new analogs with improved efficacy or reduced cardiotoxicity.
• Antitumor Agent Development: Serves as a precursor in the development of targeted cancer therapies.
• Academic Research: Employed in university and institutional labs for investigating the mechanisms of action of anthracycline derivatives.

Basic Information

Product Name	3'-(4-Methoxy-1-Piperidinyl)-3'-Deaminodaunorubicin
CAS No.	79867-76-8
Molecular Formula	C33H39NO11
Molecular Weight	625.67 g/mol
Synonyms	3'-Deamino-3'-(4-methoxy-1-piperidinyl)doxorubicin; 3'-Deamino-3'-(4-methoxy-1-piperidinyl)daunorubicin; 3'-(4-Methoxy-1-piperidyl)-3'-deaminodaunorubicin; 3'-Deamino-3'-(4-methoxy-1-piperidinyl)-13-dihydrodaunorubicin; AD 198 (related analog); 4'-O-Methyl-3'-deamino-3'-(4-methoxy-1-piperidinyl)doxorubicin; 3'-Deamino-3'-(4-methoxy-1-piperidinyl)adriamycin; 3'-(4-Methoxy-1-piperidinyl)-3'-deaminodoxorubicin
EINECS	Contact for details

Quality Control

Our 3'-(4-Methoxy-1-Piperidinyl)-3'-Deaminodaunorubicin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.