Description

Timobesone Acetate is a synthetic corticosteroid derivative with potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for the development of advanced topical and systemic therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of treatments for dermatological conditions, allergic reactions, and autoimmune disorders, ensuring precise and reliable pharmacological activity.

Application

• Pharmaceutical API: Core active ingredient in the formulation of topical creams, ointments, and lotions for treating eczema, psoriasis, and dermatitis.
• Veterinary Medicine: Used in anti-inflammatory preparations for skin conditions and allergic reactions in animals.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and new drug development.
• Advanced Dermatology: Incorporated into compounded medications for targeted, potent corticosteroid therapy.
• Immunology Research: Employed in laboratory studies to investigate mechanisms of inflammation and immune response modulation.

Basic Information

Product Name	Timobesone Acetate
CAS No.	79578-14-6
Molecular Formula	C24H31FO6
Molecular Weight	434.50 g/mol
Synonyms	9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione 21-acetate; Timobesone 21-Acetate; SQ-27239; (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione 21-acetate; Fluocortin Butyl Acetate (related compound); Corticosteroid API SQ-27239
EINECS	Contact for details

Quality Control

Our Timobesone Acetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and specific identification tests, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance with in-house specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.