Description

2-Fluoro-6-Iodobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and iodine atoms on the aromatic ring, which enables selective cross-coupling reactions and facilitates the introduction of complex functional groups. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the reactive iodine moiety.
• Chemical Biology & Proteomics: Employed as a molecular tag or probe in bioconjugation and labeling studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	2-Fluoro-6-Iodobenzonitrile
CAS No.	79544-29-9
Molecular Formula	C7H3F1I1N1
Molecular Weight	247.01 g/mol
Synonyms	2-Fluoro-6-iodobenzonitrile; 6-Iodo-2-fluorobenzonitrile; Benzonitrile, 2-fluoro-6-iodo-; 2-Fluoro-6-iodo-benzonitrile; 79544-29-9; 2-Fluoro-6-iodobenzene carbonitrile; 2-Fluoro-6-iodophenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Iodobenzonitrile is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.