Description

Methylprednisolone 17-Propionate CAS NO 79512-61-1 is a synthetic corticosteroid derivative, specifically a 17-propionate ester of methylprednisolone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, offering enhanced lipophilicity and a modified pharmacokinetic profile compared to the parent molecule. It is a critical active pharmaceutical ingredient (API) and intermediate for the development and manufacturing of advanced topical and injectable corticosteroid formulations, primarily serving the pharmaceutical and research sectors.

Application

• Pharmaceutical API: Core active ingredient in topical creams, ointments, and lotions for treating inflammatory skin conditions such as eczema, psoriasis, and dermatitis.
• Injectable Formulations: Used in the synthesis of depot injections for sustained-release anti-inflammatory therapy.
• Veterinary Medicine: Employed in anti-inflammatory and immunosuppressive treatments for animals.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological research and new drug development.
• Steroid Prodrug Synthesis: Acts as a crucial precursor for synthesizing more complex corticosteroid prodrugs with targeted delivery.

Basic Information

Product Name	Methylprednisolone 17-Propionate
CAS No.	79512-61-1
Molecular Formula	C25H34O6
Molecular Weight	430.53 g/mol
Synonyms	Methylprednisolone 17-Propionate; 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-propionate; 6α-Methylprednisolone 17-propionate; U-67590A; Medrol propionate; Methylprednisolone propionate
EINECS	Contact for details

Quality Control

Our Methylprednisolone 17-Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.