Description

(7R)-7,8,9,10-Tetrahydro-6,7β,8α,10α,11-Pentahydroxy-1-Methoxy-8β-Methyl-5,12-Naphthacenedione CAS NO 79438-99-6 is a complex, polyhydroxylated naphthacenedione derivative, a structural class known for significant biological activity. This compound matters as a high-purity chemical intermediate critical for advanced pharmaceutical research and synthesis. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anthracycline and tetracycline analogue drug candidates.
• Anticancer Research: Serves as a core scaffold for developing new chemotherapeutic agents targeting DNA intercalation and topoisomerase inhibition.
• Antibiotic Development: Used in research to create next-generation antibiotics by modifying the naphthacenedione core structure.
• Biochemical Research: Employed as a standard or probe in studies of enzyme interactions and redox biology due to its quinone moiety.
• Process Chemistry: Utilized in scaling up synthetic routes for complex natural product derivatives in pilot plant settings.
• Academic Research: A valuable compound for universities and institutes studying organic synthesis methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	(7R)-7,8,9,10-Tetrahydro-6,7β,8α,10α,11-Pentahydroxy-1-Methoxy-8β-Methyl-5,12-Naphthacenedione
CAS No.	79438-99-6
Molecular Formula	C₂₁H₂₂O₉
Molecular Weight	418.39 g/mol
Synonyms	7-Deoxy-13-dihydrodaunomycinone; 7-Deoxy-13-dihydrocarminomycinone; (7R)-7,8,9,10-Tetrahydro-6,7,8,10,11-pentahydroxy-1-methoxy-8-methyl-5,12-naphthacenedione; 7R-7,8,9,10-Tetrahydro-6,7b,8a,10a,11-pentahydroxy-1-methoxy-8b-methyl-5,12-naphthacenedione; 7-Deoxy-13-dihydrodaunorubicinone; Arugomycinone intermediate; Anthracycline intermediate
EINECS	Contact for details

Quality Control

Our (7R)-7,8,9,10-Tetrahydro-6,7β,8α,10α,11-Pentahydroxy-1-Methoxy-8β-Methyl-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.