Description

1-(2-Fluoro-5-Nitrophenyl)Ethan-1-One is a versatile fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its fluorinated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and molecular recognition studies.
• Chemical Research & Development: A fundamental building block for academic and industrial R&D in organic and fluorine chemistry.
• Dye and Pigment Intermediate: Used in the synthesis of specialized nitro- and fluoro-containing colorants.

Basic Information

Product Name	1-(2-Fluoro-5-Nitrophenyl)Ethan-1-One
CAS No.	79110-05-7
Molecular Formula	C8H6FNO3
Molecular Weight	183.14 g/mol
Synonyms	2'-Fluoro-5'-nitroacetophenone; 1-Acetyl-2-fluoro-5-nitrobenzene; 2-Fluoro-5-nitroacetophenone; 5-Nitro-2-fluoroacetophenone; Ethanone, 1-(2-fluoro-5-nitrophenyl)-; 2-Fluoro-5-nitroacetylbenzene; 1-(2-Fluoro-5-nitrophenyl)ethanone; 79110-05-7
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-Nitrophenyl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.