Description

1H-Benzimidazole,5,6-Difluoro-2-(1-Methylethyl)-(9Ci) is a high-purity, fluorinated benzimidazole derivative, a key advanced intermediate in modern organic synthesis. Its value lies in its unique molecular structure, which is critical for introducing specific pharmacological properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides, where the difluoro motif enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and organic electronic materials requiring specific fluorinated heterocyclic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1H-Benzimidazole,5,6-Difluoro-2-(1-Methylethyl)-(9Ci)
CAS No.	78582-00-0
Molecular Formula	C10H10F2N2
Molecular Weight	196.20 g/mol
Synonyms	5,6-Difluoro-2-isopropyl-1H-benzimidazole; 2-Isopropyl-5,6-difluorobenzimidazole; 5,6-Difluoro-2-(propan-2-yl)-1H-benzo[d]imidazole; 2-(1-Methylethyl)-5,6-difluoro-1H-benzimidazole; 78582-00-0; 5,6-Difluoro-2-isopropylbenzimidazole; Benzimidazole, 5,6-difluoro-2-(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole,5,6-Difluoro-2-(1-Methylethyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.