Description

Deglycobleomycin is a key derivative of the bleomycin family of glycopeptide antibiotics, specifically engineered for research into the structure-activity relationships of these compounds. Its primary value lies in its role as a critical intermediate and reference standard for the development and analysis of novel antitumor agents. This product is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on oncology drug discovery and biochemical mechanism studies.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate in the synthesis and structural modification of bleomycin analogs for enhanced therapeutic profiles.
• Biochemical Mechanism Studies: Used to investigate the DNA-cleaving activity and metal-binding properties of bleomycins, independent of their carbohydrate moiety.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for the quality control and quantification of bleomycin-related compounds in APIs and formulations.
• Academic Research: A vital tool for studying the pharmacology and toxicology of antitumor antibiotics in university and institutional labs.
• Process Development: Utilized in the scale-up and optimization of synthetic routes for bleomycin-class active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Deglycobleomycin
CAS No.	78314-57-5
Molecular Formula	C50H74N18O19S2
Molecular Weight	1271.37 g/mol
Synonyms	Deglycobleomycin A2; N1-[3-[(Aminoiminomethyl)amino]propyl]bleomycinamide; Bleomycin, deglyco-; Deglycobleomycin Hydrochloride; Antibiotic YA-56X; NSC-694279; Demethylbleomycin A2; Deglycobleomycin (Bleomycin derivative)
EINECS	Contact for details

Quality Control

Our Deglycobleomycin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing including HPLC purity assay, identity confirmation (IR, MS), and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. For long-term storage, consider storing desiccated at -20°C. Handle with appropriate precautions in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.