Description

Bisantrene is a synthetic anthracenedione derivative with significant research and development interest. This compound is valued for its unique structural and biological properties, making it a key intermediate and reference standard in advanced pharmaceutical research. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in oncology and medicinal chemistry. Our supply of Bisantrene CAS NO 78186-34-2 is characterized by high purity and batch-to-batch consistency to support critical R&D and production workflows.

Application

• Pharmaceutical Research & Development: Serves as a crucial reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel chemotherapeutic agents.
• Oncology Studies: Used in biochemical and pharmacological research to investigate mechanisms of action related to DNA intercalation and topoisomerase II inhibition.
• Medicinal Chemistry: Acts as a core scaffold or precursor for the synthesis of new chemical entities and analogs with potential therapeutic activity.
• Biochemical Assays: Employed as a standard in high-throughput screening (HTS) and in vitro studies to evaluate cytotoxicity and efficacy.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cancer biology and drug discovery.
• GMP Manufacturing: Supplied as a high-purity starting material or intermediate for cGMP-compliant production processes under controlled environments.

Basic Information

Product Name	Bisantrene
CAS No.	78186-34-2
Molecular Formula	C₂₆H₂₈N₄O₄
Molecular Weight	460.53 g/mol
Synonyms	9,10-Anthracenedione, 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-; CL 216,942; NSC 337766; Anthracenedione derivative; 1,4-Bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione; Bisantren; Bisantrene dihydrochloride (salt form)
EINECS	Contact for details

Quality Control

Every batch of Bisantrene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity (by IR and MS), and impurity profiles. Our quality commitment aligns with cGMP principles for APIs and relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.