Description

3-Fluoro-2-Methoxybenzonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it a critical intermediate for introducing specific electronic and steric properties into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure aids in tuning electronic properties.
• Organic Synthesis Reagent: A valuable starting material for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction pathways and creating novel chemical entities.

Basic Information

Product Name	3-Fluoro-2-Methoxybenzonitrile
CAS No.	77801-22-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Methoxy-3-fluorobenzonitrile; 3-Fluoro-2-methoxybenzenecarbonitrile; Benzonitrile, 3-fluoro-2-methoxy-; 3-Fluoro-o-anisonitrile; 2-Cyano-6-fluoroanisole; 6-Fluoro-2-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.