Description

N1-[3-(Cyclohexylamino)Propyl]Bleomycinamide is a chemically modified derivative of the potent antitumor antibiotic bleomycin, designed for enhanced stability and targeted research applications. This compound is of significant interest in the development of novel chemotherapeutic agents and as a key intermediate in advanced pharmaceutical synthesis. It serves as a critical research material for oncology-focused biotech firms, academic research institutions, and pharmaceutical developers engaged in anticancer drug discovery and mechanism-of-action studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation bleomycin analogs and conjugated drug candidates.
• Anticancer Research: Used as a reference standard and active component in in vitro and in vivo studies to investigate DNA cleavage mechanisms and cytotoxicity.
• Bioconjugation Studies: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its modifiable functional groups.
• Biochemical Tool Compound: Employed in molecular biology and biochemistry labs to study the effects of bleomycin-family compounds on cellular processes.
• Structure-Activity Relationship (SAR) Research: Essential for medicinal chemistry programs aiming to understand and improve the therapeutic profile of bleomycin derivatives.

Basic Information

Product Name	N1-[3-(Cyclohexylamino)Propyl]Bleomycinamide
CAS No.	77698-93-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-(cyclohexylamino)propyl]-; 3'-Amino-3'-deoxy-N1-[3-(cyclohexylamino)propyl]bleomycinamide; Bleomycin derivative (77698-93-2); Modified Bleomycin A5; Cyclohexylamino-propyl-bleomycinamide
EINECS	Contact for details

Quality Control

Our N1-[3-(Cyclohexylamino)Propyl]Bleomycinamide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and relevant analytical data. We adhere to high-purity standards suitable for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.