Description

5-(1-Hydroxy-2-(Isopropylamino)Butyl)-7-Hydroxycarbostyril is a high-purity synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on cardiovascular and respiratory drug discovery. Our supply is characterized by stringent quality control, ensuring reliability for sensitive formulation and process development work.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of β-adrenergic receptor antagonists (β-blockers) and related cardiovascular APIs.
• Active Pharmaceutical Ingredient (API): Serves as the core active moiety in finished dosage forms for targeted therapeutic applications.
• Research & Development: Essential reference standard and starting material in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for commercial pharmaceutical production.
• Analytical Standard: High-purity grade material for use in HPLC, LC-MS, and NMR as a calibration or identification standard in quality control labs.

Basic Information

Product Name	5-(1-Hydroxy-2-(Isopropylamino)Butyl)-7-Hydroxycarbostyril
CAS No.	77405-41-5
Molecular Formula	C₁₆H₂₂N₂O₃
Molecular Weight	290.36 g/mol
Synonyms	7-Hydroxy-5-[(1R)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-2(1H)-quinolinone; (R)-5-(1-Hydroxy-2-(isopropylamino)butyl)-7-hydroxycarbostyril; Celiprolol Intermediate; Celiprolol Related Compound; β-Blocker Intermediate B; CAS 77405-41-5; UNII-7V515P5N3C
EINECS	Contact for details

Quality Control

Every batch of 5-(1-Hydroxy-2-(Isopropylamino)Butyl)-7-Hydroxycarbostyril is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. A detailed Certificate of Analysis (COA), including results for identity, purity, and specified impurities, is supplied with each shipment. Our quality standards are designed to meet the requirements of cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.