Description

13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[3-[(1-Phenylethyl)Amino]Propyl]Bleomycinamide is a structurally complex, semi-synthetic derivative of the bleomycin family of glycopeptide antibiotics. This compound is of significant interest in pharmaceutical research and development due to its potential as a cytotoxic agent with a modified mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel oncology therapeutics and for studying DNA interaction mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel anti-cancer agents.
• Oncology Drug Discovery: Used in preclinical studies to investigate its cytotoxicity, mechanism of action, and structure-activity relationships (SAR) against various cancer cell lines.
• Biochemical Research: Employed as a tool compound to study DNA cleavage, oxidative damage, and the role of metal complexes in biological systems.
• Academic Research: Utilized in university and institutional labs for chemical biology studies focusing on antibiotic derivatives and their therapeutic potential.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[3-[(1-Phenylethyl)Amino]Propyl]Bleomycinamide
CAS No.	77368-80-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide derivative; 19-Demethyl bleomycin derivative; Talopyranosyl bleomycinamide; N1-[3-[(1-Phenylethyl)Amino]Propyl]bleomycinamide; Bleomycin A2 analogue; Glycopeptide antibiotic derivative; Phenylalanine-modified bleomycin; Research Compound 77368-80-0
EINECS	Contact for details

Quality Control

Our 13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[3-[(1-Phenylethyl)Amino]Propyl]Bleomycinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.