Description

13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[2-[(2-Hydroxypropyl)Amino]Ethyl]Bleomycinamide is a structurally complex bleomycin derivative, representing a key intermediate or analog in the development of advanced antitumor agents. This compound is of significant interest for its potential role in oncology research and pharmaceutical development, particularly in the study of DNA-cleaving mechanisms and the synthesis of novel chemotherapeutic candidates. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on next-generation cancer therapeutics.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel bleomycin-based anticancer drugs.
• Oncology Drug Discovery: Used in biochemical assays to investigate mechanisms of action, DNA interaction, and cytotoxicity profiles against various cancer cell lines.
• Chemical Biology Studies: Employed as a tool compound to explore structure-activity relationships (SAR) within the bleomycin family of glycopeptide antibiotics.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex molecular entities targeting specific biological pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and molecular pharmacology.
• Reference Standard Production: Manufactured under controlled conditions to serve as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[2-[(2-Hydroxypropyl)Amino]Ethyl]Bleomycinamide
CAS No.	77368-70-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide derivative; 19-Demethyl-bleomycin derivative; BLM derivative; Talopyranosyl bleomycin analog; 4-Amino-4,6-dideoxy-α-L-talopyranosyl oxy bleomycinamide; N1-[2-[(2-Hydroxypropyl)amino]ethyl]bleomycinamide derivative; Antitumor antibiotic intermediate
EINECS	Contact for details

Quality Control

Our 13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxy-N1-[2-[(2-Hydroxypropyl)Amino]Ethyl]Bleomycinamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing specifications such as assay purity and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0% Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.