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13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-N1-[4-Amino-6-Oxo-6-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Hexyl]-19-Demethyl-12-Hydroxybleomycinamide CAS NO 77368-66-2
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CAS No.:77368-66-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-N1-[4-Amino-6-Oxo-6-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Hexyl]-19-Demethyl-12-Hydroxybleomycinamide is a sophisticated semi-synthetic derivative of the bleomycin family of glycopeptide antibiotics. This compound is of significant interest for its potential in advanced pharmaceutical research and development, particularly in the study of novel mechanisms of action and structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation therapeutic agents.
Application
- Pharmaceutical Research: A key intermediate or reference standard in the development of novel anti-cancer and antimicrobial agents.
- Biochemical Studies: Used to investigate DNA cleavage mechanisms and the structural determinants of bleomycin-family activity.
- Medicinal Chemistry: Serves as a scaffold for the synthesis of new analogs with potentially improved efficacy or reduced toxicity profiles.
- Academic Research: Employed in university and institutional labs for fundamental studies in chemical biology and pharmacology.
- Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical substances.
Basic Information
| Product Name | 13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-N1-[4-Amino-6-Oxo-6-[[3-[(1-Phenylethyl)Amino]Propyl]Amino]Hexyl]-19-Demethyl-12-Hydroxybleomycinamide |
| CAS No. | 77368-66-2 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 19-Demethyl-12-hydroxybleomycinamide derivative; BLM derivative; Talopyranosyl bleomycin analog; 13-O-(4-Amino-4,6-dideoxy-α-L-talopyranosyl)-N1-[4-amino-6-oxo-6-[[3-[(1-phenylethyl)amino]propyl]amino]hexyl]-19-demethyl-12-hydroxybleomycinamide; Bleomycin A2 analog; 77368-66-2 (CAS Index Name); Antibiotic derivative 77368-66-2 |
| EINECS | Contact for details |
Quality Control
Our products undergo rigorous quality testing to ensure compliance with industry standards. Production and analysis follow strict internal protocols suitable for research-grade materials. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content | ≤ 5.0% |
| Residual Solvents | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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