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2-Amino-6-Fluorobenzonitrile CAS NO 77326-36-4


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CAS No.:77326-36-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-6-Fluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block essential for advanced organic synthesis. Its core value lies in the strategic combination of an amino group and a fluorine atom on the benzonitrile scaffold, enabling precise molecular modifications and the development of novel compounds with targeted properties. This intermediate is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
  • Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
  • Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where its aromatic and electronic properties are beneficial.
  • Fluorescent Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with specific light-absorption or emission characteristics.
  • Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated aromatic amines.

Basic Information

Product Name 2-Amino-6-Fluorobenzonitrile
CAS No. 77326-36-4
Molecular Formula C7H5FN2
Molecular Weight 136.13 g/mol
Synonyms 6-Fluoro-2-aminobenzonitrile; 2-Amino-6-fluorobenzonitrile; 6-Fluoroanthranilonitrile; 2-Cyano-3-fluoroaniline; Benzonitrile, 2-amino-6-fluoro-; 3-Fluoro-2-aminobenzonitrile; 2-Fluoro-6-aminobenzonitrile; 6-Fluoro-2-cyanoaniline
EINECS Contact for details

Quality Control

Our 2-Amino-6-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Heavy Metals < 20 ppm
Residue on Ignition < 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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