Description

2Qn-Echinomycin CAS NO 77186-00-0 is a potent, naturally derived quinoxaline antibiotic and antitumor agent. This compound is of significant interest in pharmaceutical research and development due to its unique mechanism of action as a DNA bis-intercalator. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology research, antimicrobial discovery, and molecular biology studies.

Application

• Oncology Research: Used as a reference standard and active compound in studies targeting cancer cell proliferation and apoptosis.
• Antimicrobial Agent Development: Serves as a lead compound for developing new antibiotics against resistant bacterial strains.
• Biochemical Research: Employed as a tool to study DNA-protein interactions and chromatin structure due to its bis-intercalating properties.
• Pharmaceutical Reference Standard: Used for quality control, method development, and validation in analytical laboratories.
• Mechanism of Action Studies: Applied in research to understand and elucidate pathways of hypoxia-inducible factor (HIF-1α) inhibition.
• Preclinical Drug Development: Investigated for its potential in novel therapeutic formulations and combination therapies.

Basic Information

Product Name	2Qn-Echinomycin
CAS No.	77186-00-0
Molecular Formula	C51H64N12O12S2
Molecular Weight	1101.26 g/mol
Synonyms	Echinomycin; Quinomycin A; NSC-526417; Antibiotic X 948; Levomycin; BRN 0093622; C51H64N12O12S2; Bisquinoline antibiotic
EINECS	Contact for details

Quality Control

Our 2Qn-Echinomycin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Biological Activity	Assayed and reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.