Description

Plomestane is a high-purity steroidal compound, specifically an aromatase inhibitor, with significant research and pharmaceutical interest. Its primary value lies in its role as a key intermediate and reference standard in the development of therapeutic agents targeting hormone-dependent conditions. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on oncology and endocrinology. We supply Plomestane CAS NO 77016-85-4 to the global market with a commitment to consistent quality and reliable supply chain integrity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced steroidal drugs and aromatase inhibitors.
• Reference Standard: Used for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Biochemical Research: Employed in preclinical studies to investigate aromatase enzyme activity and hormone metabolism pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the manufacturing process of final drug formulations.
• Academic & Clinical Research: Utilized in university and hospital labs for studies related to breast cancer, endometriosis, and other estrogen-modulated conditions.

Basic Information

Product Name	Plomestane
CAS No.	77016-85-4
Molecular Formula	C₂₀H₂₄O₂
Molecular Weight	296.40 g/mol
Synonyms	10β-(Propyn-1-yl)-estr-4-ene-3,17-dione; SH-489; CGS-18320B; 4,17β-Dihydroxy-4-androstene-3-one 10β-propynyl derivative; Plomestane [USAN]; (10β)-10-Propynylestr-4-ene-3,17-dione
EINECS	Contact for details

Quality Control

Our Plomestane is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets exacting standards for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting full compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.