Description

1,4-Pregnadien-11-Beta, 18,21-Diol-3,20-Dione is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical precursor in the synthesis of more complex corticosteroid derivatives, enabling the production of potent anti-inflammatory and immunosuppressive agents. It is primarily required by pharmaceutical manufacturers, advanced research institutions, and fine chemical synthesis facilities focused on developing next-generation therapeutic steroids.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent glucocorticoid drugs.
• Corticosteroid Research: Used in laboratory settings for the research and development of novel anti-inflammatory and immunosuppressive agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for specialized steroid-based compounds.
• Biochemical Studies: Utilized in metabolic pathway research and studies of steroid hormone action and receptor binding.

Basic Information

Product Name	1,4-Pregnadien-11-Beta, 18,21-Diol-3,20-Dione
CAS No.	76959-24-5
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	11β,18,21-Trihydroxy-1,4-pregnadiene-3,20-dione; 11β,18,21-Trihydroxypregna-1,4-diene-3,20-dione; 18,21-Dihydroxy-11β-hydroxypregna-1,4-diene-3,20-dione; 1,4-Pregnadiene-11β,18,21-triol-3,20-dione; Pregna-1,4-diene-11β,18,21-triol-3,20-dione
EINECS	Contact for details

Quality Control

Our 1,4-Pregnadien-11-Beta, 18,21-Diol-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.