Description

2,4,6-Trifluoro-Dl-Phenylalanine is a fluorinated derivative of the essential amino acid phenylalanine, distinguished by its unique trifluoromethyl substitution pattern. This structural modification is critical for enhancing metabolic stability, lipophilicity, and bioavailability in advanced pharmaceutical research and development. It serves as a key chiral building block and intermediate for medicinal chemists and researchers in the life sciences sector, particularly in the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and positron emission tomography (PET) tracers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Peptidomimetics & Bioactive Peptides: Used to incorporate fluorine into peptide backbones to improve proteolytic stability, membrane permeability, and receptor binding affinity.
• Agrochemical Research: Acts as a building block for developing novel fluorinated pesticides and herbicides with enhanced activity and environmental persistence.
• Positron Emission Tomography (PET) Tracer Development: Serves as a starting material for synthesizing fluorine-18 (18F) labeled compounds for non-invasive medical imaging.
• Chemical Biology & Proteomics: Employed as a molecular probe to study protein-protein interactions and enzyme mechanisms via fluorine NMR spectroscopy.
• Material Science: Potential monomer for creating specialty polymers and liquid crystals with unique electronic and surface properties.

Basic Information

Item	Details
Product Name	2,4,6-Trifluoro-Dl-Phenylalanine
CAS No.	76932-42-8
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	DL-2,4,6-Trifluorophenylalanine; (±)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid; 2,4,6-Trifluoro-DL-phenylalanine; 2,4,6-Trifluorophenylalanine, DL-; rac-2,4,6-Trifluorophenylalanine; (RS)-2-Amino-3-(2,4,6-trifluorophenyl)propionic acid; 3-(2,4,6-Trifluorophenyl)-DL-alanine; F3Phe
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluoro-Dl-Phenylalanine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-Racemate
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.