Description

4'''-Deoxy-4'''-Aminoaclacinomycin is a chemically modified derivative of the anthracycline antibiotic aclacinomycin, designed for enhanced research utility and specific biological activity. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology research, antibiotic development, and molecular biology studies.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel anthracycline-based chemotherapeutic agents.
• Oncology Studies: Investigated for its mechanism of action, cytotoxicity, and potential anti-tumor properties in various cancer cell lines.
• Biochemical Research: Used as a tool compound to study DNA intercalation, topoisomerase inhibition, and other biological pathways targeted by anthracyclines.
• Antibiotic Development: Acts as a structural analog for developing new antibiotics with modified efficacy and reduced side-effect profiles.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and pharmacology.
• API Synthesis: Functions as a building block in the multi-step synthesis of complex active pharmaceutical ingredients for preclinical and clinical trials.

Basic Information

Product Name	4'''-Deoxy-4'''-Aminoaclacinomycin
CAS No.	76439-76-4
Molecular Formula	C42H53NO16
Molecular Weight	827.87 g/mol
Synonyms	4'-Deoxy-4'-aminoaclacinomycin; 4'''-Deamino-4'''-deoxyaclacinomycin; 4'-Amino-4'-deoxyaclacinomycin; Aclacinomycin 4'''-deoxy-4'''-amine; 4'-Deoxy-4'-aminoaclacinomycin A; Antibiotic MA 144M1 derivative; 4'-Deoxy-4'-aminoaclacinomycin A; 4'''-Deoxy-4'''-aminoaclacinomycin A
EINECS	Contact for details

Quality Control

Our 4'''-Deoxy-4'''-Aminoaclacinomycin is produced under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.