Description

4-Fluoro-2-Nitrobenzyl Bromide is a versatile and reactive halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electrophilic benzyl bromide site and an electron-deficient nitro group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized aromatic monomers for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for the site-specific labeling and modification of biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis and Scale-up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects.

Basic Information

Product Name	4-Fluoro-2-Nitrobenzyl Bromide
CAS No.	76437-44-0
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	1-(Bromomethyl)-4-fluoro-2-nitrobenzene; α-Bromo-4-fluoro-2-nitrotoluene; 2-Nitro-4-fluorobenzyl Bromide; (4-Fluoro-2-nitrophenyl)methyl Bromide; 4-Fluoro-2-nitrobenzylbromide; 4-Fluoro-2-nitro-α-bromotoluene; p-Fluoro-o-nitrobenzyl Bromide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Nitrobenzyl Bromide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.