Description

[5-[3-[2-(3,4-Dimethoxyphenyl)Ethylamino]-2-Hydroxy-Propoxy]-2-Oxo-3,4-Dihydro-1H-Quinolin-8-Yl]Urea Hydrochloride is a high-purity synthetic organic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular structure, featuring a quinolinone core linked to a dimethoxyphenethylamino side chain, makes it a valuable intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways. This compound is primarily sought by R&D chemists and process development scientists within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for potential Active Pharmaceutical Ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Preclinical Studies: Utilized in in-vitro and in-vivo studies to assess the pharmacokinetic and pharmacodynamic properties of new chemical entities.

Basic Information

Product Name	[5-[3-[2-(3,4-Dimethoxyphenyl)Ethylamino]-2-Hydroxy-Propoxy]-2-Oxo-3,4-Dihydro-1H-Quinolin-8-Yl]Urea Hydrochloride
CAS No.	76412-48-1
Molecular Formula	C23H29ClN4O6
Molecular Weight	493.95 g/mol
Synonyms	Carvedilol Impurity 11; Carvedilol Related Compound H; 8-[[3-[2-(3,4-Dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]-2-oxo-3,4-dihydro-1H-quinolin-5-yl]urea hydrochloride; Urea, N-[8-[[3-[2-(3,4-dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]-2-oxo-3,4-dihydro-1H-quinolin-5-yl]-, monohydrochloride; Carvedilol EP Impurity H; Carvedilol USP Impurity H
EINECS	Contact for details

Quality Control

Our [5-[3-[2-(3,4-Dimethoxyphenyl)Ethylamino]-2-Hydroxy-Propoxy]-2-Oxo-3,4-Dihydro-1H-Quinolin-8-Yl]Urea Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.