Description

Diprosone Depot is a high-purity synthetic corticosteroid, specifically a potent glucocorticoid, widely recognized for its anti-inflammatory and immunosuppressive properties. Its depot formulation is engineered for sustained release, making it a critical active pharmaceutical ingredient (API) for long-acting therapeutic applications. This compound is essential for manufacturers in the global pharmaceutical industry developing injectable and topical formulations targeting chronic inflammatory and dermatological conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in long-acting injectable corticosteroid formulations.
• Dermatological Preparations: Key component in creams, ointments, and lotions for treating psoriasis, eczema, and other severe skin inflammations.
• Rheumatology & Orthopedics: Used in intra-articular and soft tissue injections for managing inflammation in conditions like bursitis, arthritis, and tendinitis.
• Ophthalmic Solutions: Incorporated into eye drops and ointments for treating inflammatory eye disorders.
• Veterinary Medicine: Applied in anti-inflammatory treatments for companion animals and livestock.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological research and new drug development.

Basic Information

Product Name	Diprosone Depot
CAS No.	76391-71-4
Molecular Formula	C28H37FO7
Molecular Weight	504.59 g/mol
Synonyms	Betamethasone Dipropionate (USP); Betamethasone 17,21-Dipropionate; 9α-Fluoro-16β-methylprednisolone 17,21-dipropionate; Diprosone; Celestoderm-V; Betnovate; Diprolene; Alphatrex; Uticort; (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
EINECS	Contact for details

Quality Control

Our Diprosone Depot is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes rigorous analytical testing including HPLC for assay and related substances, residual solvent analysis, and comprehensive identification tests. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment to ensure full traceability and quality assurance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Specific Rotation	+99° to +105°
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.