Description

N1-(4-Aminobutyl)-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide is a structurally complex bleomycin derivative, representing a high-value intermediate or active pharmaceutical ingredient (API) in advanced pharmaceutical research and development. This compound is critical for investigating novel mechanisms of action and developing next-generation therapeutic agents, particularly in oncology. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and academic research institutions focused on anticancer drug discovery and molecular biology studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel bleomycin-based chemotherapeutic agents.
• Anticancer Drug Discovery: Used in biological assays to evaluate efficacy, mechanism of action, and structure-activity relationships (SAR) against various cancer cell lines.
• Biochemical Research: Employed as a tool compound to study DNA cleavage, oxidative damage mechanisms, and cellular response to genotoxic stress.
• Reference Standard Manufacturing: Supplied as a high-purity certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Preclinical Studies: Utilized in pharmacokinetic, pharmacodynamic, and toxicology studies during the early stages of drug candidate development.

Basic Information

Item	Details
Product Name	N1-(4-Aminobutyl)-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide
CAS No.	76069-32-4
Molecular Formula	C₅₇H₉₂N₂₀O₂₁S₂
Molecular Weight	Contact for details
Synonyms	19-Demethyl-12-hydroxybleomycinamide; Bleomycin derivative; Bleomycin A2 derivative; Talopyranosyl bleomycin; 4-Amino-4,6-dideoxy-α-L-talopyranosyl bleomycin; BLM derivative; N1-(4-Aminobutyl)bleomycinamide; Pharmaceutical Intermediate 76069-32-4
EINECS	Contact for details

Quality Control

Our N1-(4-Aminobutyl)-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. Certificates of Analysis (COA) detailing purity by HPLC, related substances, and other critical parameters are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.