Description

13-Deoxocarminomycin is a key anthracycline derivative and structural analog of the potent anticancer agent carminomycin. This compound serves as a critical intermediate and reference standard in pharmaceutical research and development, particularly for the synthesis and study of novel chemotherapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery, mechanism of action studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A vital building block in the synthetic pathway for novel anthracycline-based anticancer drugs.
• Biochemical Research: Used as a reference standard to study the structure-activity relationships (SAR) of anthracycline antibiotics and their interaction with DNA.
• Analytical Standard: Serves as a high-purity calibrant for quality control (QC) and analytical method validation (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Oncology R&D: Employed in preclinical research to investigate the mechanisms, efficacy, and potential modifications of anthracycline chemotherapeutics to reduce cardiotoxicity.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological studies related to topoisomerase II inhibition.

Basic Information

Product Name	13-Deoxocarminomycin
CAS No.	76034-18-9
Molecular Formula	C26H27NO10
Molecular Weight	513.49 g/mol
Synonyms	13-Deoxycarminomycin; 7-Deoxycarminomycin; 13-Demethoxycarminomycin; 4-Demethoxy-13-deoxydaunorubicin; Carminomycin I 13-deoxy derivative; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Every batch of 13-Deoxocarminomycin is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.