Description

Butanedioic Acid, Fluoro-, Dimethyl Ester, (R)- (9Ci) is a chiral fluorinated succinate derivative, serving as a high-value synthetic intermediate. This compound matters for its role in introducing both fluorine atoms and stereochemical control into complex molecular architectures, enabling the development of novel materials and bioactive compounds. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis and fluorination chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral, fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where the fluorine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Fluorine Chemistry Research: An essential reagent in academic and industrial R&D for studying new fluorination methodologies and creating fluorinated molecular probes.
• Advanced Material Monomer: Potential monomer for creating specialty polymers with unique optical, electronic, or surface properties due to the fluorine content.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial production of fine chemicals requiring this specific chiral motif.

Basic Information

Product Name	Butanedioic Acid, Fluoro-, Dimethyl Ester, (R)- (9Ci)
CAS No.	76003-45-7
Molecular Formula	C6H9FO4
Molecular Weight	164.13 g/mol
Synonyms	(R)-2-Fluorobutanedioic Acid Dimethyl Ester; Dimethyl (R)-2-Fluorobutanedioate; (R)-2-Fluorodimethyl Succinate; (R)-Dimethyl 2-Fluorobutanedioate; (R)-2-Fluorodimethyl Succinate; (R)-2-Fluorosuccinic Acid Dimethyl Ester; (R)-Dimethyl 2-Fluorosuccinate; (R)-Methyl Hydrogen 2-Fluorobutanedioate (related)
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, Fluoro-, Dimethyl Ester, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% (R)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.