Description

2-Difluoromethoxy-2,2-difluoroacetic acid is a specialized fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its unique difluoromethoxy and difluoroacetic acid structure makes it a valuable precursor for introducing fluorine-containing motifs, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity, stability, and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in high-performance liquid crystal displays (LCDs).
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: A versatile reagent for synthesizing complex fluorinated compounds in academic and industrial research laboratories.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to improve performance and safety characteristics.

Basic Information

Item	Detail
Product Name	2-Difluoromethoxy-2,2-difluoroacetic Acid
CAS No.	75780-06-2
Molecular Formula	C3H2F4O3
Molecular Weight	162.04 g/mol
Synonyms	Difluoromethoxydifluoroacetic Acid; 2,2-Difluoro-2-(difluoromethoxy)acetic Acid; Acetic acid, 2,2-difluoro-2-(difluoromethoxy)-; (Difluoromethoxy)difluoroacetic Acid; α,α-Difluoro-α-(difluoromethoxy)acetic Acid; DFMDFA; 75780-06-2
EINECS	Contact for details

Quality Control

Every batch of 2-Difluoromethoxy-2,2-difluoroacetic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.