Description

4'-Epidaunomycin is a significant anthracycline derivative and a key intermediate in pharmaceutical research and synthesis. This compound is valued for its structural role in the development of novel chemotherapeutic agents and for biochemical studies exploring mechanisms of action. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology drug discovery and advanced chemical synthesis. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex anthracycline-based anticancer drugs.
• Biochemical Research: Used in studies to investigate DNA intercalation mechanisms, topoisomerase II inhibition, and cellular apoptosis pathways.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, and NMR for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A key starting material for structural modification and SAR (Structure-Activity Relationship) studies to develop new analogs with improved efficacy or reduced toxicity.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and oncology.

Basic Information

Product Name	4'-Epidaunomycin
CAS No.	75444-29-0
Molecular Formula	C26H29NO10
Molecular Weight	515.51 g/mol
Synonyms	4'-Epi-daunomycin; 4'-Epidoxorubicin; 4'-Epidau; (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; 4'-Epi-DNR; 4'-epi-Daunorubicin; Daunorubicin 4'-epimer
EINECS	Contact for details

Quality Control

Our 4'-Epidaunomycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.