Description

Saframycin S is a potent antibiotic compound belonging to the saframycin family, a class of natural products known for their significant biological activity. This compound is valued in research and development for its unique mechanism of action, which involves DNA interaction and topoisomerase inhibition. It is primarily utilized by pharmaceutical researchers and biotechnology companies engaged in the discovery of novel anti-infective and anticancer agents, as well as in biochemical studies exploring cellular processes.

Application

• Research and development of novel antibiotic and antitumor agents.
• Biochemical studies investigating mechanisms of DNA intercalation and topoisomerase inhibition.
• Use as a reference standard in analytical method development and quality control for pharmaceutical research.
• Exploration in combinatorial chemistry and medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Potential application in the synthesis of more complex bioactive molecules or drug conjugates.

Basic Information

Item	Detail
Product Name	Saframycin S
CAS No.	75425-66-0
Molecular Formula	C27H30N4O7
Molecular Weight	522.55 g/mol
Synonyms	Saframycin S; Antibiotic C 15003P3; NSC 339586; 1,2,3,4,6,11,12,12a-Octahydro-2,7-dimethyl-8,10-bis(methylamino)-6,12a-epoxy-1,5,12-trioxonaphthacene-9-carboxylic acid methyl ester; C15003P3; NSC-339586
EINECS	Contact for details

Quality Control

Our Saframycin S is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.