Description

(R)-(+)-Carteolol CAS NO 75331-19-0 is the pharmacologically active enantiomer of carteolol, a non-selective β-adrenergic receptor blocking agent. This high-purity chiral intermediate is critical for the development and manufacturing of enantiomerically pure pharmaceuticals, ensuring targeted therapeutic efficacy and minimizing side effects. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers specializing in cardiovascular and ophthalmic medications.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of (R)-Carteolol hydrochloride, the active ingredient in β-blocker medications.
• Cardiovascular Drug Research: Used in preclinical and clinical studies for developing new β-adrenergic antagonists to treat hypertension and angina.
• Ophthalmic Solution Development: Serves as a precursor in formulating enantiopure drugs for treating glaucoma by reducing intraocular pressure.
• Chiral Catalyst & Ligand Synthesis: Utilized in asymmetric synthesis research to create novel catalysts for stereoselective reactions.
• Analytical Reference Standard: Provides a certified standard for quality control and regulatory testing (HPLC, chiral analysis) in pharmaceutical manufacturing.
• Metabolite Studies: Employed in pharmacological research to investigate the metabolic pathways and pharmacokinetics of carteolol.

Basic Information

Product Name	(R)-(+)-Carteolol
CAS No.	75331-19-0
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	(R)-Carteolol; (+)-Carteolol; (R)-(+)-5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone; (R)-1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-4-oxoquinolin-5-yl)oxy]-2-propanol; (-)-1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-4-oxoquinolin-5-yl)oxy]-2-propanol (enantiomer); AR-C 119000; OPC-1085 enantiomer
EINECS	Contact for details

Quality Control

Our (R)-(+)-Carteolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided and can be tailored to support regulatory filings (e.g., FDA, EMA).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.