Description

5-Chloro-2-Fluorobenzyl Cyanide is a versatile and high-purity fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for constructing complex heterocycles and exploring new reaction pathways in medicinal chemistry.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	5-Chloro-2-Fluorobenzyl Cyanide
CAS No.	75279-54-8
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	2-Fluoro-5-chlorobenzyl cyanide; (5-Chloro-2-fluorophenyl)acetonitrile; 5-Chloro-2-fluorobenzeneacetonitrile; 2-Fluoro-5-chlorobenzeneacetonitrile; α-Cyano-5-chloro-2-fluorotoluene; (2-Fluoro-5-chlorophenyl)acetonitrile; 75279-54-8; 5-Chloro-2-fluoro-α-tolunitrile
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-Fluorobenzyl Cyanide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.