Description

(8R)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,10β,11-Tetrahydroxy-5,12-Naphthacenedione CAS NO 74978-24-8 is a high-purity, structurally defined naphthacenedione derivative, a class of compounds known for their significant biological and chemical activity. This compound matters for its role as a critical synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents and analytical method development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anthracycline and tetracycline analogs with potential therapeutic applications.
• Reference Standard: High-purity material for use in analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Tool compound for studying enzyme interactions, DNA intercalation, and structure-activity relationships (SAR) in medicinal chemistry programs.
• Fine Chemical Synthesis: Precursor for the development of specialized dyes, pigments, and advanced organic materials requiring a complex polycyclic quinone core.
• Academic Research: Used in university and institutional labs for investigations into organic synthesis methodologies and the properties of polyhydroxylated naphthacenediones.

Basic Information

Product Name	(8R)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,10β,11-Tetrahydroxy-5,12-Naphthacenedione
CAS No.	74978-24-8
Molecular Formula	C₂₀H₂₀O₆
Molecular Weight	356.37 g/mol
Synonyms	8-Ethyl-7,8,9,10-tetrahydro-1,6,10b,11-tetrahydroxy-5,12-naphthacenedione; (8R)-8-Ethyl-7,8,9,10-tetrahydro-1,6,10b,11-tetrahydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,10b,11-tetrahydroxy-, (8R)-; 74978-24-8; Naphthacenedione derivative; Tetrahydroxynaphthacenedione
EINECS	Contact for details

Quality Control

Our (8R)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,10β,11-Tetrahydroxy-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.