Description

Alanylleucyl-Daunorubicin is a synthetic peptide conjugate of the anthracycline antibiotic daunorubicin, designed for targeted therapeutic applications. This compound is of significant interest in advanced pharmaceutical research due to its potential for enhanced specificity and reduced systemic toxicity compared to its parent molecule. It is primarily utilized by research institutions and pharmaceutical developers focusing on novel oncology treatments and targeted drug delivery systems.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active component in the development of novel, targeted anti-cancer therapeutics.
• Oncology Drug Discovery: Used in preclinical studies to investigate mechanisms of action, efficacy, and pharmacokinetics of peptide-drug conjugates.
• Targeted Drug Delivery Systems: Employed in the design of prodrugs and conjugates that aim to selectively deliver cytotoxic agents to tumor cells.
• Biochemical Research: Acts as a tool compound for studying enzyme-substrate interactions, particularly those involving peptide cleavage and drug release mechanisms.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and molecular pharmacology.

Basic Information

Product Name	Alanylleucyl-Daunorubicin
CAS No.	74853-81-9
Molecular Formula	C41H53N5O13
Molecular Weight	823.89 g/mol
Synonyms	Ala-Leu-Daunorubicin; N-(N-L-Alanyl-L-leucyl)daunorubicin; Daunorubicin alanylleucine conjugate; L-Alanyl-L-leucyldaunorubicin; Ala-Leu-DNR; Peptide-daunorubicin conjugate; Daunorubicin peptide derivative
EINECS	Contact for details

Quality Control

Our Alanylleucyl-Daunorubicin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade chemicals, ensuring data integrity for your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, maintain desiccated conditions.

Specification

Item	Specification
Appearance	Red to orange-red solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤3.0%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.