Description

4-(5-Hydroxydibenzo[A,D]Cyclohepten-5-Yl)-4-Methylpiperidinium Chloride CAS NO 74499-08-4 is a high-purity organic salt with a complex, fused-ring structure, serving as a critical advanced pharmaceutical intermediate. Its primary value lies in enabling the synthesis of sophisticated active pharmaceutical ingredients (APIs) for targeted therapeutic applications. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or receptor-targeted therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with specific pharmacological properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-(5-Hydroxydibenzo[A,D]Cyclohepten-5-Yl)-4-Methylpiperidinium Chloride
CAS No.	74499-08-4
Molecular Formula	C21H24ClNO
Molecular Weight	341.87 g/mol
Synonyms	4-(5-Hydroxydibenzo[a,d]cyclohepten-5-yl)-4-methylpiperidinium chloride; 4-Methyl-4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidinium chloride; 5-(4-Methyl-4-piperidinio)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol chloride; Desmethylcyproheptadine chlorohydrate; Norcyproheptadine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(5-Hydroxydibenzo[A,D]Cyclohepten-5-Yl)-4-Methylpiperidinium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.