Description

n-Formyl-1-Hydroxy-13-Dihydrodaunomycin is a key chemical intermediate and derivative of the anthracycline class, specifically related to daunorubicin. This compound is of significant interest for its role in the research and development of novel pharmaceutical agents, particularly in oncology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules and potential chemotherapeutic candidates.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel anthracycline derivatives and analogs for anticancer drug discovery.
• Biochemical Research: Used as a reference standard or probe in studies investigating the structure-activity relationships (SAR) of daunorubicin and related compounds.
• Academic Research: Employed in university and institutional labs for fundamental research on DNA intercalation, topoisomerase inhibition, and mechanisms of action of anthracycline antibiotics.
• Process Development: Serves as a key intermediate for process chemists developing scalable and efficient synthetic routes for complex active pharmaceutical ingredients (APIs).
• Metabolite Studies: Potential use in the study of metabolic pathways and biotransformation products of daunorubicin and similar chemotherapeutic agents.

Basic Information

Product Name	n-Formyl-1-Hydroxy-13-Dihydrodaunomycin
CAS No.	74273-37-3
Molecular Formula	C27H29NO10
Molecular Weight	527.52 g/mol
Synonyms	1-Hydroxy-13-dihydrodaunomycin N-formyl derivative; 13-Dihydrodaunorubicin N-formyl-1-hydroxy derivative; 1-Hydroxy-13-dihydro-N-formyldaunomycin; Daunorubicin derivative, N-formyl-1-hydroxy-13-dihydro; 7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[(2,3,6-trideoxy-3-formamido-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our n-Formyl-1-Hydroxy-13-Dihydrodaunomycin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.