Description

16Alpha,17,21-Trihydroxypregna-4,9(11)-Diene-3,20-Dione 21-Acetate is a high-purity steroid derivative, specifically a key synthetic intermediate in the production of advanced pharmaceutical compounds. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing potent glucocorticoids and other bioactive molecules. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on steroid-based therapeutics and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid drugs, such as anti-inflammatory and immunosuppressive agents.
• Research & Development: Used in medicinal chemistry for the discovery and development of new steroid-based therapeutics targeting specific biological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid manufacturing within GMP environments.
• Biochemical Research: Utilized in studies investigating steroid hormone metabolism, receptor binding, and enzyme inhibition.

Basic Information

Product Name	16Alpha,17,21-Trihydroxypregna-4,9(11)-Diene-3,20-Dione 21-Acetate
CAS No.	74220-43-2
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	9(11)-Dehydrocortisol 21-Acetate; 16α,17,21-Trihydroxy-9(11)-dehydropregn-4-ene-3,20-dione 21-Acetate; 16α-Hydroxy-9(11)-dehydrocortisol 21-Acetate; 16α-Hydroxyprednisolone 21-Acetate; (16α)-11-Dehydro-17,21-dihydroxypregn-4-ene-3,20-dione 21-acetate; 16α-Hydroxy-9(11)-dehydrocorticosterone 21-acetate
EINECS	Contact for details

Quality Control

Our 16Alpha,17,21-Trihydroxypregna-4,9(11)-Diene-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.