Description

Mitomycin G is a potent antibiotic and antitumor agent belonging to the mitomycin family of compounds. It is valued in research and development for its unique mechanism of action, which involves DNA alkylation and cross-linking, leading to the inhibition of DNA synthesis. This compound is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in oncology drug discovery and biochemical studies.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel chemotherapeutic agents.
• Biochemical Research: Used as a tool compound in molecular biology to study DNA damage and repair mechanisms, apoptosis, and cell cycle arrest.
• Anticancer Agent Studies: Investigation of structure-activity relationships (SAR) within the mitomycin class to develop more effective or less toxic derivatives.
• Academic Research: Serves as a critical reagent in university and institutional labs for cancer biology and pharmacology projects.
• Quality Control: Employed as a high-purity analytical standard for the identification and quantification of mitomycin compounds in pharmaceutical quality assurance.

Basic Information

Product Name	Mitomycin G
CAS No.	74148-46-2
Molecular Formula	C16H21N3O6
Molecular Weight	351.36 g/mol
Synonyms	7-Aminomitomycin; 7-Amino-9a-methoxy-1a,2,8,8a,9,9a-hexahydro-4,7-dihydroxy-8-(hydroxymethyl)-6-methoxy-1,2,9-trioxa-5-azacyclopenta[b]naphthalene-3-carboxamide; FR-900482; Antibiotic FR-900482; Mitomycin G (FR-900482)
EINECS	Contact for details

Quality Control

Our Mitomycin G is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is light-sensitive and should be handled accordingly to maintain potency.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.