Description

Ticabesone CAS NO 74131-77-4 is a synthetic corticosteroid compound known for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of advanced topical and systemic pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of treatments for dermatological conditions, allergic reactions, and autoimmune disorders.

Application

• Pharmaceutical API: Core active ingredient in the manufacture of topical creams, ointments, and lotions for treating eczema, psoriasis, and dermatitis.
• Veterinary Medicine: Used in formulations for managing inflammatory skin conditions and allergic reactions in animals.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and new drug development programs.
• Compounding Pharmacy: Utilized by specialized pharmacies for preparing customized medication formulations for specific patient needs.
• Anti-inflammatory Preparations: Integral to the production of injectable or oral medications targeting severe inflammation and immune system modulation.

Basic Information

Product Name	Ticabesone
CAS No.	74131-77-4
Molecular Formula	C24H31FO6
Molecular Weight	434.50 g/mol
Synonyms	9-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β,21-dihydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; Ticabeson; Tiabesone; SQ-27239; Flucortin butyl ester (related); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ticabesone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) detailing specifications for identity, purity, and impurities, referencing relevant pharmacopeial guidelines. Our commitment to cGMP compliance and supply chain integrity guarantees product consistency and traceability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.