Description

[[2-[3-(Trifluoromethyl)Phenyl]-2-Methoxyethyl]Amino]Acetonitrile is a specialized organic intermediate featuring a trifluoromethylphenyl moiety and an aminoacetonitrile functional group, offering unique reactivity for advanced chemical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce fluorinated aromatic systems into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the metabolic stability imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine-containing aromatic ring enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags or molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	[[2-[3-(Trifluoromethyl)Phenyl]-2-Methoxyethyl]Amino]Acetonitrile
CAS No.	74051-09-5
Molecular Formula	C₁₂H₁₃F₃N₂O
Molecular Weight	258.24 g/mol
Synonyms	2-[[2-[3-(Trifluoromethyl)phenyl]-2-methoxyethyl]amino]acetonitrile; 2-({2-[3-(Trifluoromethyl)phenyl]-2-methoxyethyl}amino)acetonitrile; 2-[[2-Methoxy-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetonitrile; Aminoacetonitrile, N-[2-methoxy-2-[3-(trifluoromethyl)phenyl]ethyl]-; N-(2-Methoxy-2-(3-(trifluoromethyl)phenyl)ethyl)aminoacetonitrile; (2-Methoxy-2-(3-trifluoromethylphenyl)ethylamino)acetonitrile; 74051-09-5; α-Methoxy-α-(3-trifluoromethylbenzyl)aminoacetonitrile
EINECS	Contact for details

Quality Control

Our [[2-[3-(Trifluoromethyl)Phenyl]-2-Methoxyethyl]Amino]Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided and available upon request. We support development and scale-up with custom purity grades to meet specific project requirements from research to commercial production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.