Description

N1-(20-Amino-6,13,20-Triimino-5,7,12,14,19-Pentaazaicosan-1-Yl)Bleomycinamide is a structurally complex, semi-synthetic derivative of the bleomycin family of glycopeptide antibiotics. This compound is of significant interest for its potential role in advanced pharmaceutical research and development, particularly in the study of novel therapeutic mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and the synthesis of specialized biochemical probes. The material is supplied under stringent quality controls to ensure consistency for critical research applications.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and synthesis of new anti-cancer agents.
• Biochemical Probe Synthesis: Used to create labeled or modified compounds for studying DNA interaction and cleavage mechanisms.
• Oncology Drug Discovery: Investigated for its potential to enhance the efficacy or alter the selectivity of bleomycin-based chemotherapeutics.
• Academic Research: Employed in university and institutional labs for fundamental studies on glycopeptide antibiotic activity and structure-activity relationships (SAR).
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	N1-(20-Amino-6,13,20-Triimino-5,7,12,14,19-Pentaazaicosan-1-Yl)Bleomycinamide
CAS No.	73666-80-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-(20-amino-6,13,20-triimino-5,7,12,14,19-pentaazaicosan-1-yl)-; 73666-80-5; Bleomycin derivative; Pentaazaicosan Bleomycinamide; N1-modified Bleomycin; Research Grade Bleomycinamide
EINECS	Contact for details

Quality Control

Our N1-(20-Amino-6,13,20-Triimino-5,7,12,14,19-Pentaazaicosan-1-Yl)Bleomycinamide is produced and handled under a strict quality management system to ensure batch-to-batch consistency and purity suitable for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) guidelines for pharmaceutical intermediates, and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a cool, dry place, ideally under controlled room temperature (15-25°C). For long-term storage, consider desiccated conditions. Handle with appropriate personal protective equipment in a well-ventilated laboratory setting.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.