Description

Ticabesone Propionate is a synthetic corticosteroid ester, a potent active pharmaceutical ingredient (API) with significant anti-inflammatory and immunosuppressive properties. Its value lies in its targeted efficacy for treating severe dermatological conditions, offering a high-potency therapeutic option. This compound is essential for pharmaceutical manufacturers and R&D laboratories developing advanced topical formulations for the global healthcare market.

Application

• Topical Corticosteroid Formulations: Primary use in high-potency creams, ointments, and lotions for treating severe psoriasis, eczema, and dermatitis.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of more complex steroid-based APIs.
• Veterinary Medicine: Used in topical preparations for managing inflammatory skin conditions in animals.
• Clinical Research: Employed as a reference standard in analytical method development and pharmacological studies.
• Dermatological R&D: Investigated for novel drug delivery systems to enhance localized efficacy and reduce systemic exposure.

Basic Information

Product Name	Ticabesone Propionate
CAS No.	73205-13-7
Molecular Formula	C25H33FO6
Molecular Weight	448.53 g/mol
Synonyms	9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 17-propionate 21-acetate; Ticabesone 17-propionate; SQ-27239; Fluocinolone Acetonide related compound; (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 17-propionate 21-acetate
EINECS	Contact for details

Quality Control

Our Ticabesone Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and control of related substances and residual solvents, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) documenting full compliance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.